![]() A second blood screen at 15 to 20 weeks refines the risk more accurately. It gives an accurate risk profile very early. The newer integrated screen (formerly called F.A.S.T.E.R for First And Second Trimester Early Results) can be done at 10 plus weeks to 13 plus weeks with an ultrasound of the fetal neck (thicker nuchal skin correlates with higher risk of Down syndrome being present) and two chemicals (analytes), pregnancy-associated plasma protein A and human chorionic gonadotropin (pregnancy hormone level itself ). Genetic screening for Down syndrome (trisomy 21) and Edwards syndrome (trisomy 18), the national standard in the United States, is rapidly evolving away from the AFP- quad screen, done typically in the second trimester at 16–18 weeks. ![]() Testing for chlamydia (and gonorrhea when indicated.Rapid plasma reagin test to screen for syphilis.Indirect Coombs test (AGT) to assess risk of hemolytic disease of the newborn.Rh-negative antenatal patients should receive RhoGAM at 28 weeks to prevent Rh disease.Routine tests in the first trimester of pregnancy generally include: ![]()
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